Blood Biomarkers Detect Amyloid in Down Syndrome Independent of APOE Status

MedAI Digest
MedAI Digest
Blood Biomarkers Detect Amyloid in Down Syndrome Independent of APOE Status
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A new blood test reliably detects amyloid positivity in adults with Down syndrome, with performance independent of APOE ε4 carrier status—offering a scalable screening approach for Alzheimer’s-related pathology.

Original paper: The association between APOE ε4 carrierships and the detection of amyloid positivity using an Alzheimer’s disease proteomic blood test in asymptomatic Down syndrome. — Alzheimer’s & dementia: the journal of the Alzheimer’s Association. 10.1002/alz.71338

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