Current medical AI articles

Original Title: Clinical Manifestations Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association DOI: 10.1002/alz70857_102378 Overview The clinical interview is the primary diagnostic gateway for identifying dementia, serving as a screening phase to determine if a patient requires intensive neurological evaluation. While large language models excel in general text processing, their utility in…

Original Title: Dementia Care Research and Psychosocial Factors Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association DOI: 10.1002/alz70858_104857 Overview The research investigates the role of artificial intelligence in supporting individuals working with Subjective Cognitive Decline (SCD), Mild Cognitive Impairment (MCI), or early-onset dementia. Employment retention is a significant challenge for this population,…

Original Title: Dementia Care Research and Psychosocial Factors Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association DOI: 10.1002/alz70858_100300 Overview OverviewThis study investigates the utility of Real-Time Location Systems (RTLS) in inpatient dementia care units to monitor behavioral and psychological symptoms. While these systems are primarily deployed for safety and nurse calls, the…

Original Title: Dementia Care Research and Psychosocial Factors Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association DOI: 10.1002/alz70858_099304 Overview This study investigates caregiver perspectives on the dementia diagnostic process and the introduction of artificial intelligence (AI) technologies. Current pathways rely on pen-and-paper assessments and informant reports, which are often perceived as insufficient…

Original Title: Clinical Manifestations Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association DOI: 10.1002/alz70857_101996 Overview This study evaluates the clinical performance of ChatGPT version 3.5 in diagnosing neurodegenerative diseases. Building on previous research where the model achieved a 45.1% accuracy rate on neurology residency exams, this investigation uses nine case reports from…

Original Title: Basic Science and Pathogenesis Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association DOI: 10.1002/alz70855_107196 Overview This research presents the development of the Alzheimer's Cell Atlas, a comprehensive resource for understanding the molecular mechanisms of neurodegenerative diseases at the level of individual cells. The study utilized single-nuclei RNA-sequencing data from 2,239…

Original Title: Basic Science and Pathogenesis Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association DOI: 10.1002/alz70855_107413 Overview Alzheimer’s disease research increasingly relies on polygenic risk scores to estimate individual susceptibility based on thousands of genetic variants. However, as genomic data expands, researchers face hurdles in reconciling results from studies with different ancestral…

Original Title: Dementia Care Research and Psychosocial Factors Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association DOI: 10.1002/alz70858_099100 Overview This study investigates how individuals with cognitive symptoms and their care partners prefer to receive and share health information after undergoing biomarker testing for Alzheimer's disease and related dementias. Utilizing a mixed-methods approach,…

Original Title: Biomarkers Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association DOI: 10.1002/alz70856_100619 Overview Alzheimer's disease presents a significant global health challenge, with early detection being a priority for effective intervention. This study investigates the use of retinal optical coherence tomography (OCT) as a non-invasive biomarker for Alzheimer's disease. The researchers developed…

Original Title: Biomarkers Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association DOI: 10.1002/alz70856_100574 Overview Alzheimer’s disease is a heterogeneous condition often occurring alongside cerebral small vessel disease. This study examines 262 individuals across two cohorts: the longitudinal TRIAD cohort, representing a low burden of small vessel disease, and the MITNEC-C6 cohort, which…