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VarNet-T: Deep Learning Brings Precision to Tumor-Only Cancer Variant Detection
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VarNet-T, a deep learning framework, substantially improves identification of cancer mutations from tumor-only sequencing data, achieving up to 33% better accuracy than existing methods and enabling more reliable patient stratification for immunotherapy.
Original paper: Improved tumor-only variant calling and mutation burden estimation with VarNet-T. — Nature communications. 10.1038/s41467-026-71705-4
